ADVACAN 0.25MG 10T

ADVACAN 0.25mg Tablet contains the active substance Everolimus 0.25mg. It belongs to a group of medicines known as mTOR Inhibitors (Immunosuppressants and Anti-Cancer Medicines). It is primarily used for the prevention of organ transplant rejection in kidney, liver, and heart transplant patients. It is also used in the treatment of certain cancers, including breast cancer, kidney cancer, pancreatic neuroendocrine tumors, and specific lung tumors.

Everolimus works by suppressing the body's immune response and inhibiting abnormal cell growth. In transplant patients, it prevents the immune system from attacking the transplanted organ, while in cancer patients it helps slow tumor growth.

Uses of ADVACAN 0.25mg Tablet

• Prevention of Organ Transplant Rejection
• Kidney Transplant Management
• Liver Transplant Management
• Heart Transplant Management
• Advanced Kidney Cancer
• Advanced Breast Cancer
• Pancreatic Neuroendocrine Tumors
• Certain Types of Lung Cancer
• Tuberous Sclerosis Complex-Associated Tumors

Therapeutic Effects of ADVACAN 0.25mg Tablet

ADVACAN works by blocking a protein called mTOR (Mammalian Target of Rapamycin), which plays an important role in cell growth, division, and immune system activity. By inhibiting this pathway, it helps prevent transplant rejection and slows the growth of cancer cells.

Interaction of ADVACAN 0.25mg Tablet with Other Drugs

It is important to inform your healthcare professional about all medicines you are taking.

Notable interactions include:

• Ketoconazole
• Rifampicin
• Carbamazepine
• Phenytoin
• Cyclosporine
• Tacrolimus
• Methotrexate
• Insulin and Anti-Diabetic Medicines
• Live Vaccines

More Information about ADVACAN 0.25mg Tablet

• Keep out of reach of children.
• Store at room temperature.
• Protect from moisture and direct sunlight.
• Keep tablets in original packaging.
• Do not use expired medication.

How to Consume ADVACAN 0.25mg Tablet

ADVACAN is an oral medicine that should be swallowed whole with water.

• Take exactly as prescribed by your doctor.
• Do not crush, chew, or break the tablet.
• Take it at the same time every day.
• It may be taken with or without food, but remain consistent in how you take it.
• Avoid grapefruit and grapefruit juice during treatment.

Safety Advice for ADVACAN 0.25mg Tablet

Breast Feeding

Not Recommended

May pass into breast milk and could harm the baby.

Alcohol

Caution

Consult your doctor before consuming alcohol during treatment.

Liver

Caution

Dose adjustment may be required in patients with liver disease. Not recommended in severe liver impairment.

Kidneys

Generally Safe

Usually no dose adjustment is required in kidney disease.

Driving

Caution

May cause fatigue, dizziness, or weakness. Avoid driving if affected.

Pregnancy

Not Recommended

May cause harm to the unborn baby. Effective contraception is recommended during treatment.

Side Effects of ADVACAN 0.25mg Tablet

Common Side Effects of ADVACAN 0.25mg Tablet

• Mouth Ulcers
• Fatigue
• Diarrhea
• Nausea
• Rash
• Weight Loss
• Joint Pain
• Taste Changes
• Anemia

Serious Side Effects of ADVACAN 0.25mg Tablet

• Severe Infections
• Pneumonitis (Lung Inflammation)
• Kidney Failure
• Severe Allergic Reactions
• Angioedema
• Pulmonary Edema
• Severe Breathing Difficulties

Word of Advice

Regular monitoring of blood counts, kidney function, liver function, cholesterol levels, and blood sugar levels is essential during ADVACAN therapy. Because this medicine suppresses the immune system, patients should avoid exposure to infections and should not receive live vaccines without medical advice. Contact your doctor immediately if you develop fever, persistent cough, breathing problems, severe mouth ulcers, or signs of infection.

FAQs about ADVACAN 0.25mg Tablet

Q1. What is ADVACAN 0.25mg Tablet used for?

It is used to prevent organ transplant rejection and to treat certain cancers.

Q2. How does ADVACAN work?

It blocks the mTOR pathway, reducing immune activity and slowing abnormal cell growth.

Q3. Can ADVACAN increase infection risk?

Yes. Since it suppresses the immune system, it may increase susceptibility to infections.

Q4. Can I take grapefruit juice while using ADVACAN?

No. Grapefruit products can increase drug levels and increase the risk of side effects.

Q5. Is regular monitoring required?

Yes. Blood tests and organ function monitoring are essential during treatment.

Fact Box of ADVACAN 0.25mg Tablet

Molecule Name: Everolimus 0.25mg

Therapeutic Class: Immunosuppressant / Anti-Cancer Medicine

Pharmacological Class: mTOR Inhibitor

Indications: Organ Transplant Rejection Prevention, Kidney Cancer, Breast Cancer, Pancreatic Neuroendocrine Tumors, Lung Cancer, Tuberous Sclerosis Complex-Associated Tumors.