APRECAP 150mg Injection contains the active substance Fosaprepitant 150mg, which is converted into Aprepitant in the body. It belongs to a group of medicines known as Neurokinin-1 (NK1) Receptor Antagonists (Antiemetics). It is primarily used to prevent chemotherapy-induced nausea and vomiting (CINV) and is often administered along with other antiemetic medicines before cancer treatment.
APRECAP works by blocking the action of Substance P (Neurokinin-1) in the brain, a chemical messenger responsible for triggering nausea and vomiting. This helps cancer patients tolerate chemotherapy more comfortably and improves treatment adherence.
APRECAP 150mg Injection is administered only by a healthcare professional as an intravenous infusion and should not be self-administered.
Uses of APRECAP 150mg Injection
- Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV)
- Prevention of Delayed Nausea and Vomiting after Chemotherapy
- Prevention of Postoperative Nausea and Vomiting (PONV)
- Supportive Care During Cancer Treatment
Therapeutic Effects of APRECAP 150mg Injection
APRECAP blocks NK1 receptors in the brain and prevents Substance P from activating the vomiting center. This action effectively controls both acute and delayed nausea and vomiting associated with chemotherapy.
Interaction of APRECAP 150mg Injection with Other Drugs
It is important to inform your healthcare professional about all medicines you are taking.
Notable interactions include:
- Warfarin
- Rifampicin
- Phenytoin
- Carbamazepine
- Ketoconazole
- Diltiazem
- Oral Contraceptives
- Corticosteroids (Dose adjustment may be required)
More Information about APRECAP 150mg Injection
- Keep out of reach of children.
- Store in a refrigerator at 2°C–8°C.
- Do not freeze.
- Protect from direct sunlight.
- For hospital and clinical use only.
How to Consume APRECAP 150mg Injection
APRECAP 150mg Injection is administered as an intravenous (IV) infusion by a doctor or nurse.
It is generally given before chemotherapy treatment to prevent nausea and vomiting. The exact schedule and dosage are determined by the treating oncologist.
Safety Advice for APRECAP 150mg Injection
Breast Feeding
Consult Your Doctor
Information regarding use during breastfeeding is limited.
Alcohol
Consult Your Doctor
The interaction with alcohol is not well established.
Liver
Caution
Patients with liver disease should use this medicine under medical supervision.
Kidneys
Caution
Use carefully in patients with severe kidney disease. Dose monitoring may be required.
Driving
Unsafe
May cause dizziness, drowsiness, or reduced alertness. Avoid driving if affected.
Pregnancy
Use Only on Medical Advice
Should be used during pregnancy only if clearly needed and prescribed by a doctor.
Side Effects of APRECAP 150mg Injection
Common Side Effects of APRECAP 150mg Injection
- Headache
- Fatigue
- Hiccups
- Constipation
- Loss of Appetite
- Indigestion
- Dizziness
- Diarrhea
Serious Side Effects of APRECAP 150mg Injection
- Severe Allergic Reactions
- Breathing Difficulties
- Severe Skin Reactions
- Liver Function Abnormalities
- Severe Dizziness or Fainting
Word of Advice
APRECAP 150mg Injection is highly effective in preventing nausea and vomiting caused by chemotherapy and is often used as part of a combination antiemetic regimen. Patients should inform their doctor about all current medications to avoid drug interactions. Seek immediate medical attention if severe allergic reactions, breathing difficulties, or persistent side effects occur. Regular liver function monitoring may be recommended during treatment.
FAQs about APRECAP 150mg Injection
Q1. What is APRECAP 150mg Injection used for?
It is used to prevent nausea and vomiting caused by chemotherapy and certain surgical procedures.
Q2. How does APRECAP work?
It blocks Neurokinin-1 (NK1) receptors and prevents nausea and vomiting signals from reaching the brain.
Q3. Is APRECAP chemotherapy?
No. It is an antiemetic medicine used to prevent chemotherapy-related side effects.
Q4. How is APRECAP administered?
It is given as an intravenous infusion by a healthcare professional before chemotherapy treatment.
Q5. Can APRECAP cause dizziness?
Yes. Dizziness and drowsiness are known side effects, so patients should avoid driving if affected.
Fact Box of APRECAP 150mg Injection
Molecule Name: Fosaprepitant 150mg
Therapeutic Class: Antiemetic Medicines
Pharmacological Class: Neurokinin-1 (NK1) Receptor Antagonist
Indications: Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV), Delayed Chemotherapy-Related Vomiting, Postoperative Nausea and Vomiting.
