BOSENTAS 62.5MG 10T

BOSENTAS 62.5mg Tablet contains the active substance Bosentan. It belongs to a group of medicines known as Endothelin Receptor Antagonists (ERAs). It is primarily indicated for the treatment of Pulmonary Arterial Hypertension (PAH), a condition characterized by high blood pressure in the arteries of the lungs.

Bosentan works by blocking the action of endothelin, a naturally occurring substance that causes blood vessels to narrow. By relaxing and widening the blood vessels in the lungs, it helps improve blood flow, reduce pressure in the pulmonary arteries, and enhance exercise capacity.

BOSENTAS 62.5mg Tablets should be used only under the supervision of a qualified healthcare professional with regular monitoring of liver function.

Uses of BOSENTAS 62.5mg Tablets

• Treatment of Pulmonary Arterial Hypertension (PAH)
• Improvement of exercise capacity in PAH patients
• Reduction of pulmonary vascular resistance
• Management of symptoms associated with pulmonary hypertension
• Prevention of worsening PAH-related complications

Therapeutic Effects of BOSENTAS 62.5mg Tablets

BOSENTAS 62.5mg Tablets work by blocking endothelin-A and endothelin-B receptors. This reduces blood vessel constriction and abnormal cell growth within pulmonary arteries. The result is improved blood circulation through the lungs, reduced pulmonary artery pressure, better oxygen delivery, and enhanced physical activity tolerance.

Interaction of BOSENTAS 62.5mg Tablets with Other Drugs

It is important to inform your healthcare professional about all medications you are taking, including prescription medicines, supplements, and herbal products.

Notable interactions include:

• Cyclosporine: Significantly increases Bosentan levels and should generally be avoided.
• Glibenclamide: Increased risk of liver toxicity.
• Warfarin: May require monitoring of anticoagulant response.
• Sildenafil: May alter blood concentrations of both medicines.
• Hormonal Contraceptives: Bosentan may reduce their effectiveness.
• Rifampicin: May reduce Bosentan effectiveness.

More Information about BOSENTAS 62.5mg Tablets

• Keep out of reach of children and pets.
• Store below 30°C in a cool and dry place.
• Protect from moisture and direct sunlight.
• Do not use expired medication.
• Regular liver function monitoring is recommended during therapy.

How to Consume BOSENTAS 62.5mg Tablets

BOSENTAS 62.5mg Tablets are oral medications meant to be swallowed whole with a glass of water. They may be taken with or without food.

Take the medicine exactly as prescribed by your doctor. The dosage may be adjusted based on your response to treatment and overall medical condition.

Safety Advice for BOSENTAS 62.5mg Tablets

Breast Feeding

Unsafe / Not Recommended

Breastfeeding is generally not recommended while taking Bosentan due to potential risks to the infant.

Alcohol

Caution

Alcohol may increase the risk of liver-related side effects and should be consumed cautiously.

Liver

Caution

Bosentan may cause liver injury. Regular liver function tests are essential during treatment.

Kidneys

Caution

Patients with kidney disease should use this medicine under medical supervision.

Driving

Caution

The medicine may cause dizziness or fatigue in some patients. Avoid driving if affected.

Pregnancy

Unsafe / Contraindicated

Bosentan can cause serious birth defects and fetal harm. Effective contraception should be used during treatment.

Side Effects of BOSENTAS 62.5mg Tablets

Side effects are unwanted symptoms caused by medicines. Although not everyone experiences them, some patients may develop side effects.

Common Side Effects of BOSENTAS 62.5mg Tablets

• Headache
• Dizziness
• Flushing
• Swelling of legs and ankles
• Nasal congestion
• Fatigue

Serious Side Effects of BOSENTAS 62.5mg Tablets

• Severe liver toxicity
• Significant reduction in hemoglobin levels (anemia)
• Severe allergic reactions
• Fluid retention
• Worsening shortness of breath
• Serious skin reactions

Word of Advice

Patients receiving BOSENTAS 62.5mg Tablets should undergo regular liver function tests and blood count monitoring throughout treatment. Women of childbearing age should use reliable contraception due to the risk of serious fetal harm. Report symptoms such as yellowing of the skin, dark urine, severe fatigue, or unexplained swelling to your doctor immediately.

FAQs about BOSENTAS 62.5mg Tablets

Q1. What is BOSENTAS 62.5mg Tablet used for?

It is primarily used for the treatment of Pulmonary Arterial Hypertension (PAH) and helps improve exercise capacity and blood flow through the lungs.

Q2. How does BOSENTAS work?

It blocks endothelin receptors, helping relax blood vessels in the lungs and reducing pulmonary artery pressure.

Q3. Why are regular liver tests required during treatment?

Bosentan can affect liver function, making periodic monitoring essential for patient safety.

Q4. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose.

Q5. Can BOSENTAS be used during pregnancy?

No. Bosentan is contraindicated during pregnancy because it may cause serious harm to the unborn baby.

Fact Box of BOSENTAS 62.5mg Tablets

Molecule Name: Bosentan 62.5mg

Therapeutic Class: Cardiovascular & Pulmonary Medicines

Pharmacological Class: Endothelin Receptor Antagonists (ERAs)

Indications: Pulmonary Arterial Hypertension (PAH), Improvement of Exercise Capacity, Reduction of Pulmonary Artery Pressure, Management of Pulmonary Vascular Disorders.