Aprepitant works by blocking the action of Substance P, a natural chemical in the brain that triggers nausea and vomiting. By preventing these signals, it helps patients tolerate chemotherapy more comfortably.
APRECAP 125mg Capsule should be taken exactly as prescribed by an oncologist or healthcare professional experienced in cancer care.
Uses of APRECAP 125mg Capsule
- Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV)
- Prevention of Delayed Nausea and Vomiting after Chemotherapy
- Prevention of Postoperative Nausea and Vomiting (PONV) in selected patients
- Supportive Care During Cancer Treatment
Therapeutic Effects of APRECAP 125mg Capsule
APRECAP blocks NK1 receptors in the brain and prevents Substance P from triggering the vomiting center. This action helps reduce both immediate and delayed nausea and vomiting associated with chemotherapy treatment.
Interaction of APRECAP 125mg Capsule with Other Drugs
It is important to inform your healthcare professional about all medicines you are taking.
Notable interactions include:
- Warfarin
- Oral Contraceptive Pills
- Rifampicin
- Ketoconazole
- Phenytoin
- Carbamazepine
- Ritonavir
- Corticosteroids (Dose adjustments may be required)
More Information about APRECAP 125mg Capsule
- Keep out of reach of children.
- Store below 30°C.
- Protect from moisture and direct sunlight.
- Keep capsules in original packaging.
- Do not use expired medication.
How to Consume APRECAP 125mg Capsule
APRECAP is an oral capsule that should be swallowed whole with water.
- Usually taken 1 hour before chemotherapy on Day 1.
- May be followed by lower-dose capsules on subsequent days as prescribed.
- Can be taken with or without food.
- Do not crush, chew, or open the capsule.
Safety Advice for APRECAP 125mg Capsule
Breast Feeding
Caution
Use during breastfeeding only if advised by your doctor.
Alcohol
Consult Your Doctor
The interaction with alcohol is not clearly established.
Liver
Caution
Patients with liver disease may require close monitoring and dose adjustments.
Kidneys
Generally Safe
Usually no dose adjustment is required in kidney disease.
Driving
Caution
May cause dizziness, drowsiness, or reduced alertness. Avoid driving if affected.
Pregnancy
Use Only on Medical Advice
Consult your doctor before use during pregnancy.
Side Effects of APRECAP 125mg Capsule
Common Side Effects of APRECAP 125mg Capsule
- Headache
- Fatigue
- Constipation
- Indigestion
- Loss of Appetite
- Hiccups
- Dizziness
- Increased Liver Enzymes
Serious Side Effects of APRECAP 125mg Capsule
- Severe Allergic Reactions
- Anaphylaxis
- Severe Skin Reactions
- Liver Dysfunction
- Breathing Difficulties
- Facial Swelling
Word of Advice
APRECAP 125mg Capsule is highly effective in preventing chemotherapy-related nausea and vomiting when taken as prescribed. It is usually used along with other antiemetic medicines such as ondansetron and dexamethasone. Inform your doctor immediately if you develop severe allergic reactions, yellowing of the skin or eyes, persistent vomiting, or unusual fatigue. Regular monitoring may be required in patients with liver disease.
FAQs about APRECAP 125mg Capsule
Q1. What is APRECAP 125mg Capsule used for?
It is used to prevent nausea and vomiting caused by chemotherapy and certain surgical procedures.
Q2. How does APRECAP work?
It blocks Substance P from binding to NK1 receptors in the brain, reducing nausea and vomiting signals.
Q3. Can APRECAP treat nausea that has already started?
No. It is mainly used to prevent nausea and vomiting before they occur.
Q4. When should APRECAP be taken?
Typically, one capsule is taken about 1 hour before chemotherapy treatment begins.
Q5. Can APRECAP be taken with food?
Yes. It may be taken with or without food as directed by your doctor.
Fact Box of APRECAP 125mg Capsule
Molecule Name: Aprepitant 125mg
Therapeutic Class: Antiemetic Medicines
Pharmacological Class: Neurokinin-1 (NK1) Receptor Antagonist
Indications: Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV), Delayed Chemotherapy-Related Vomiting, Postoperative Nausea and Vomiting.
