BIOVORIN 15mg Tablet contains the active substance Leucovorin Calcium (Folinic Acid). It belongs to a group of medicines known as folate analogs. It is primarily used to reduce the harmful effects of certain chemotherapy medicines such as methotrexate and to treat folic acid deficiency when conventional folic acid therapy is not appropriate.
Leucovorin works by supplying the body with a biologically active form of folic acid, helping healthy cells recover from the toxic effects of certain medications while allowing cancer treatment to remain effective.
Uses of BIOVORIN 15mg Tablets
- Rescue therapy after high-dose Methotrexate treatment
- Treatment of folate deficiency states
- Reduction of toxicity caused by folic acid antagonists
- Supportive treatment in certain cancer therapies
- Adjunct therapy in colorectal cancer treatment along with fluorouracil (5-FU)
Therapeutic Effects of BIOVORIN 15mg Tablets
BIOVORIN 15mg Tablets help restore folate levels in the body and protect normal cells from the toxic effects of medications that interfere with folic acid metabolism. It reduces bone marrow suppression, gastrointestinal toxicity, and other complications associated with high-dose methotrexate therapy while supporting normal cellular function.
Interaction of BIOVORIN 15mg Tablets with Other Drugs
It is important to inform your healthcare professional about all medications you are taking, including prescription medicines, supplements, and herbal products.
Notable interactions include:
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Methotrexate: May reduce toxicity when administered according to prescribed schedules.
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Fluorouracil (5-FU): May enhance the therapeutic and toxic effects of fluorouracil.
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Phenytoin: May reduce blood levels and effectiveness of phenytoin.
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Phenobarbital: May decrease anticonvulsant activity.
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Primidone: May reduce seizure control in some patients.
More Information about BIOVORIN 15mg Tablets
- Keep out of reach of children.
- Store below 25°C in a cool and dry place.
- Protect from moisture and direct sunlight.
- Do not use after the expiry date.
How to Consume BIOVORIN 15mg Tablets
BIOVORIN 15mg Tablets should be taken exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water. It may be taken with or without food.
The dosage and duration depend on the condition being treated and the patient's response to therapy. Follow your doctor's instructions carefully, especially when used alongside chemotherapy medications.
Safety Advice for BIOVORIN 15mg Tablets
Breast Feeding
Caution
Consult your doctor before using this medicine while breastfeeding.
Alcohol
Caution
Alcohol should be consumed cautiously as it may interfere with overall treatment outcomes.
Liver
Caution
Patients with liver disease should use this medicine under medical supervision.
Kidneys
Caution
Dose adjustments may be required in patients with kidney impairment.
Driving
Safe
BIOVORIN generally does not affect the ability to drive or operate machinery.
Pregnancy
Use Only on Medical Advice
Use during pregnancy only if clearly needed and prescribed by a healthcare professional.
Side Effects of BIOVORIN 15mg Tablets
Side effects are unwanted symptoms caused by medicines. Although not everyone experiences them, some patients may develop side effects.
Common Side Effects of BIOVORIN 15mg Tablets
- Nausea
- Vomiting
- Mild stomach discomfort
- Loss of appetite
- Fatigue
Serious Side Effects of BIOVORIN 15mg Tablets
- Severe allergic reactions
- Difficulty breathing
- Skin rash and swelling
- Severe gastrointestinal disturbances
- Seizure-related complications in susceptible individuals
Word of Advice
BIOVORIN 15mg Tablets are often used as part of specialized treatment protocols, especially during chemotherapy. Never alter the prescribed dose or schedule without consulting your doctor. Regular medical monitoring may be necessary to ensure optimal treatment effectiveness and safety.
FAQs about BIOVORIN 15mg Tablets
Q1. What is BIOVORIN 15mg Tablet used for?
It is primarily used to reduce the toxic effects of methotrexate therapy and to treat certain folate deficiency conditions.
Q2. Is BIOVORIN the same as folic acid?
No. BIOVORIN contains Leucovorin (Folinic Acid), which is an active form of folate and works differently from standard folic acid supplements.
Q3. Can BIOVORIN be taken with chemotherapy?
Yes. It is commonly prescribed alongside certain chemotherapy medicines under specialist supervision.
Q4. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue normally. Do not double the dose.
Q5. Can BIOVORIN prevent methotrexate side effects?
Yes. When prescribed appropriately, it helps reduce the toxic effects associated with high-dose methotrexate treatment.
Fact Box of BIOVORIN 15mg Tablets
Molecule Name: Leucovorin Calcium 15mg (Folinic Acid)
Therapeutic Class: Vitamins & Nutritional Supplements / Antidotes
Pharmacological Class: Reduced Folate Derivatives
Indications: Methotrexate Rescue Therapy, Folate Deficiency, Adjunct Cancer Therapy, Reduction of Antifolate Toxicity.
