{"product_id":"adcyclo-50-tablets","title":"Adcyclo 50 Tablets","description":"\u003ch2 data-path-to-node=\"5\"\u003eIntroduction to Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cp data-path-to-node=\"6\"\u003eAdcyclo 50 Tablet contains the active substance Cyclophosphamide. It belongs to a group of medicines known as alkylating agents, which function as cytostatic antineoplastics and potent immunosuppressants. It is widely indicated for the treatment of various malignant diseases, including malignant lymphomas (Hodgkin's disease, non-Hodgkin's lymphoma), multiple myeloma, leukemias (acute and chronic lymphocytic\/myelogenous leukemia), neuroblastoma, adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. Additionally, it is used as a non-neoplastic immunosuppressant for adult and pediatric patients with severe, progressive autoimmune diseases, such as lupus nephritis and severe rheumatoid arthritis, or to treat minimal change nephrotic syndrome in pediatric patients who are unresponsive to steroid therapies.\u003c\/p\u003e\n\u003cp data-path-to-node=\"7\"\u003eCyclophosphamide is a prodrug that must be metabolized by liver enzymes into its active forms (phosphoramide mustard and acrolein). The active compounds cross-link with the strands of DNA within rapidly dividing cells, preventing DNA replication and causing cell death. This targeted disruption prevents the proliferation of malignant cancer cells and overactive, autoreactive immune cells (T and B lymphocytes), resulting in tumor regression and decreased autoimmune inflammation.\u003c\/p\u003e\n\u003cp data-path-to-node=\"8\"\u003eAdcyclo 50 Tablets must be used under the strict supervision of an oncologist, hematologist, or nephrologist experienced in chemotherapeutic agents. The dosage and duration are strictly calculated based on the patient's therapeutic indication, body weight, liver function, and hematological baseline counts.\u003c\/p\u003e\n\u003cp data-path-to-node=\"9\"\u003eBefore starting treatment, inform your healthcare professional if you have severe bone marrow suppression, active infections, urinary tract blockages, a history of hemorrhagic cystitis (bladder inflammation with bleeding), liver disease, or kidney impairment. Seek immediate emergency medical care if you notice blood in your urine, painful urination, a high fever, severe chills, unusual bruising, or persistent respiratory distress.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"10\"\u003eUses of Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cp data-path-to-node=\"11\"\u003eUses of Adcyclo 50 Tablets:\u003c\/p\u003e\n\u003cul data-path-to-node=\"12\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,0,0\"\u003eCombination chemotherapy regimens for malignant lymphomas, breast cancer, ovarian cancer, and leukemias.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,1,0\"\u003eTreatment of minimal change nephrotic syndrome in pediatric patients when corticosteroid therapies fail or cause severe side effects.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"12,2,0\"\u003eManagement of severe, life-threatening autoimmune conditions like lupus nephritis, Wegener's granulomatosis, and severe rheumatoid arthritis (off-label\/specialized use).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"13\"\u003eTherapeutic Effects of Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cp data-path-to-node=\"14\"\u003eAdcyclo 50 Tablets exert their therapeutic effect via powerful alkylation mechanisms. Once activated by the liver's cytochrome P450 system, the drug's active metabolites bind directly to the guanine bases of DNA, creating structural cross-links. This cross-linking process permanently locks the DNA strands together, preventing the cell from unzipping its genetic structure to replicate. Consequently, rapidly multiplying malignant structures and inflammatory white blood cells are forced into apoptosis (programmed cell death), bringing tumor expansion or severe immune-mediated organ damage to a halt.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"15\"\u003eInteraction of Adcyclo 50 Tablets with other drugs\u003c\/h2\u003e\n\u003cp data-path-to-node=\"16\"\u003eIt is important to inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, nutritional supplements, and herbal products. Some medications may interact with Adcyclo 50 Tablets, potentially affecting their effectiveness or causing serious side effects. Notable interactions include:\u003c\/p\u003e\n\u003cul data-path-to-node=\"17\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,0,0\"\u003e\u003cb data-path-to-node=\"17,0,0\" data-index-in-node=\"0\"\u003eAllopurinol:\u003c\/b\u003e Gout medication that can significantly increase bone marrow suppression when taken concurrently with Cyclophosphamide.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,1,0\"\u003e\u003cb data-path-to-node=\"17,1,0\" data-index-in-node=\"0\"\u003eDigoxin:\u003c\/b\u003e Cyclophosphamide can impair the gastrointestinal absorption of digoxin tablets, lowering its effectiveness for heart conditions.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,2,0\"\u003e\u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"0\"\u003eSuccinylcholine:\u003c\/b\u003e Cyclophosphamide reduces plasma pseudocholinesterase levels, which can cause prolonged neuromuscular blockage and extended respiratory depression during anesthesia.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"17,3,0\"\u003e\u003cb data-path-to-node=\"17,3,0\" data-index-in-node=\"0\"\u003eDoxorubicin \/ Trastuzumab:\u003c\/b\u003e Combined use with cyclophosphamide increases the risk of cardiotoxicity (heart muscle stress).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"18\"\u003eMore Information about Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cul data-path-to-node=\"19\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,0,0\"\u003eKeep out of reach of children and pets.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,1,0\"\u003eStore in a cool, dry place at a temperature not exceeding 25°C.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"19,2,0\"\u003eAvoid exposing the product to excessive heat, as cyclophosphamide tablets can degrade if kept above room temperature.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"20\"\u003eHow to consume Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cp data-path-to-node=\"21\"\u003eAdcyclo 50 Tablets are oral medications meant to be swallowed whole with a glass of water. Do not crush, chew, or split the tablets. Take the medicine exactly as directed by your physician. It is highly recommended to take your dose \u003cb data-path-to-node=\"21\" data-index-in-node=\"233\"\u003eearly in the morning\u003c\/b\u003e. Taking it late in the day allows the active drug metabolites to sit in your bladder overnight, drastically increasing the risk of bladder toxicity. You must drink large amounts of water (at least 2 to 3 liters) throughout the day of your dose and empty your bladder frequently to flush out drug residues.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"22\"\u003eSafety Advice for Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003ch3 data-path-to-node=\"23\"\u003eBreast Feeding\u003c\/h3\u003e\n\u003cp data-path-to-node=\"24\"\u003e\u003cb data-path-to-node=\"24\" data-index-in-node=\"0\"\u003eUnsafe \/ Contraindicated\u003c\/b\u003e Cyclophosphamide passes directly into human breast milk and can cause profound bone marrow suppression, severe chemical toxicities, and developmental issues in a nursing child. Breasting must be strictly discontinued during treatment.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"25\"\u003eAlcohol\u003c\/h3\u003e\n\u003cp data-path-to-node=\"26\"\u003e\u003cb data-path-to-node=\"26\" data-index-in-node=\"0\"\u003eUnsafe\u003c\/b\u003e Avoid alcohol while taking Adcyclo 50 Tablets. Alcohol heavily stresses the liver, compounding the risk of hepatotoxicity and interfering with the metabolic activation of the drug.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"27\"\u003eLiver\u003c\/h3\u003e\n\u003cp data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eCaution\u003c\/b\u003e Cyclophosphamide relies entirely on the liver for its conversion into active components. Patients with pre-existing hepatic impairment require precise clinical evaluation and altered dosing schedules. Frequent liver function tests (LFTs) are necessary.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"29\"\u003eLungs\u003c\/h3\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003eCaution\u003c\/b\u003e Cyclophosphamide can rarely cause pulmonary fibrosis or interstitial lung disease during long-term therapy. Report any new or worsening cough, breathlessness, or chest discomfort to your physician immediately.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"31\"\u003eDriving\u003c\/h3\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eConsult Your Doctor\u003c\/b\u003e Adcyclo 50 Tablets can cause nausea, dizziness, or generalized weakness in some patients. If you experience these symptoms, avoid driving or operating heavy machinery until you feel completely alert.\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"33\"\u003ePregnancy\u003c\/h3\u003e\n\u003cp data-path-to-node=\"34\"\u003e\u003cb data-path-to-node=\"34\" data-index-in-node=\"0\"\u003eUnsafe \/ Contraindicated\u003c\/b\u003e This medication is highly teratogenic and genotoxic. It can cause severe birth defects, fetal mutations, and miscarriage. Both male and female patients must use reliable, strict contraceptive methods during treatment and for at least 6 months after stopping the drug.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"35\"\u003eSide Effects of Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cp data-path-to-node=\"36\"\u003eSide effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them.\u003c\/p\u003e\n\u003cp data-path-to-node=\"37\"\u003eCommon side effects of Adcyclo 50 Tablets are:\u003c\/p\u003e\n\u003cul data-path-to-node=\"38\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"38,0,0\"\u003eComplete or partial hair loss (alopecia)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"38,1,0\"\u003eSevere nausea, vomiting, and loss of appetite\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"38,2,0\"\u003eDiarrhea or abdominal discomfort\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"38,3,0\"\u003eDarkening of the skin or nails\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"38,4,0\"\u003eGeneral fatigue or weakness\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"39\"\u003eSerious side effects of Adcyclo 50 Tablets are:\u003c\/p\u003e\n\u003cul data-path-to-node=\"40\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"40,0,0\"\u003e\u003cb data-path-to-node=\"40,0,0\" data-index-in-node=\"0\"\u003eHemorrhagic Cystitis:\u003c\/b\u003e (Blood in urine, severe bladder pain, painful burning during urination).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"40,1,0\"\u003e\u003cb data-path-to-node=\"40,1,0\" data-index-in-node=\"0\"\u003eSevere Bone Marrow Suppression:\u003c\/b\u003e (Extreme drop in white blood cells leading to high fever, severe sore throat, sudden pale skin, bleeding gums, or easy bruising).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"40,2,0\"\u003e\u003cb data-path-to-node=\"40,2,0\" data-index-in-node=\"0\"\u003eCardiotoxicity:\u003c\/b\u003e (Swelling in the ankles, rapid heart palpitations, severe breathlessness at rest).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"40,3,0\"\u003e\u003cb data-path-to-node=\"40,3,0\" data-index-in-node=\"0\"\u003eSecondary Malignancies:\u003c\/b\u003e (Increased long-term risk of developing urinary bladder or blood cancers).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"41\"\u003eWord of Advice\u003c\/h2\u003e\n\u003cp data-path-to-node=\"42\"\u003eAlways remember that hydration is your primary shield against bladder damage while on Adcyclo 50 Tablets. Never delay urinating; empty your bladder immediately when you feel the urge to minimize the time drug metabolites stay in contact with your bladder walls. Ensure you undergo all weekly or bi-weekly complete blood counts (CBC) ordered by your care team to check your white blood cell levels. Stay away from large crowds or individuals with contagious illnesses like flu or chickenpox, as your body's immune defense lines will be lowered during therapy.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"43\"\u003eFAQs about Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cp data-path-to-node=\"44\"\u003e\u003cb data-path-to-node=\"44\" data-index-in-node=\"0\"\u003eQ1. Why is it vital to drink so much water and pass urine frequently while taking Adcyclo?\u003c\/b\u003e When your liver breaks down Cyclophosphamide, it produces a chemical byproduct called acrolein. Acrolein travels to your bladder and can severely irritate and damage the bladder lining, causing a condition called hemorrhagic cystitis (bleeding from the bladder). Drinking plenty of fluids and emptying your bladder often dilutes the acrolein and flushes it out quickly.\u003c\/p\u003e\n\u003cp data-path-to-node=\"45\"\u003e\u003cb data-path-to-node=\"45\" data-index-in-node=\"0\"\u003eQ2. Will my hair grow back after completing treatment with Adcyclo 50 Tablets?\u003c\/b\u003e Yes. Hair loss or thinning is a very common side effect of Cyclophosphamide, often affecting the scalp, eyebrows, and eyelashes. However, this effect is temporary, and your hair will normally begin to grow back a few months after your treatment course is completely finished.\u003c\/p\u003e\n\u003cp data-path-to-node=\"46\"\u003e\u003cb data-path-to-node=\"46\" data-index-in-node=\"0\"\u003eQ3. Can Adcyclo 50 Tablets affect my fertility and ability to have children?\u003c\/b\u003e Yes, Cyclophosphamide can cause permanent or temporary infertility in both men and women by interfering with sperm production and ovarian function. If you plan to have children in the future, discuss fertility preservation options (such as sperm or egg banking) with your doctor before starting your first dose.\u003c\/p\u003e\n\u003cp data-path-to-node=\"47\"\u003e\u003cb data-path-to-node=\"47\" data-index-in-node=\"0\"\u003eQ4. What should I do if I see blood in my urine while taking this medicine?\u003c\/b\u003e If you see visible pink or red blood in your urine, or if a routine urine test reveals microscopic blood, stop taking the medication and contact your oncologist or healthcare provider immediately. This is a primary sign of bladder irritation that requires immediate clinical assessment.\u003c\/p\u003e\n\u003cp data-path-to-node=\"48\"\u003e\u003cb data-path-to-node=\"48\" data-index-in-node=\"0\"\u003eQ5. Can I take standard painkillers like ibuprofen or aspirin for aches while on Adcyclo?\u003c\/b\u003e No, you should consult your doctor first. Drugs like aspirin and ibuprofen can increase your risk of bleeding and stomach irritation, which can be dangerous if Adcyclo has already lowered your blood platelet counts. Your doctor will provide a safe alternative for pain management.\u003c\/p\u003e\n\u003ch2 data-path-to-node=\"49\"\u003eFact Box of Adcyclo 50 Tablets\u003c\/h2\u003e\n\u003cul data-path-to-node=\"50\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"50,0,0\"\u003e\u003cb data-path-to-node=\"50,0,0\" data-index-in-node=\"0\"\u003eMolecule name:\u003c\/b\u003e Cyclophosphamide (50mg)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"50,1,0\"\u003e\u003cb data-path-to-node=\"50,1,0\" data-index-in-node=\"0\"\u003eTherapeutic class:\u003c\/b\u003e Antineoplastics \/ Cytotoxic Immunosuppressants\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"50,2,0\"\u003e\u003cb data-path-to-node=\"50,2,0\" data-index-in-node=\"0\"\u003ePharmacological class:\u003c\/b\u003e Nitrogen Mustard Alkylating Agents\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"50,3,0\"\u003e\u003cb data-path-to-node=\"50,3,0\" data-index-in-node=\"0\"\u003eIndications:\u003c\/b\u003e 1. Treatment of lymphomas, myelomas, leukemias, and solid carcinomas. 2. Treatment of steroid-resistant minimal change nephrotic syndrome in pediatric patients. 3. Severe, progressive autoimmune conditions like lupus nephritis.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 data-path-to-node=\"51\"\u003eReferences\u003c\/h2\u003e\n\u003col start=\"1\" data-path-to-node=\"52\"\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"52,0,0\"\u003eEmadi A, et al. Cyclophosphamide: Then and now. \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003ca rel=\"noopener\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19632349\/\" class=\"ng-star-inserted\" data-hveid=\"0\" data-ved=\"0CAAQ_4QMahgKEwjixcTjm8KUAxUAAAAAHQAAAAAQ2gQ\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/19632349\/\u003c\/a\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"52,1,0\"\u003eMoore MJ. Clinical pharmacokinetics of cyclophosphamide. \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.google.com\/search?q=https:\/\/pubmed.ncbi.nlm.nih.gov\/1921386\/\" class=\"ng-star-inserted\" data-hveid=\"0\" data-ved=\"0CAAQ_4QMahgKEwjixcTjm8KUAxUAAAAAHQAAAAAQ2wQ\" target=\"_blank\"\u003ehttps:\/\/pubmed.ncbi.nlm.nih.gov\/1921386\/\u003c\/a\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"52,2,0\"\u003eNational Comprehensive Cancer Network (NCCN). Clinical Practice Guidelines in Oncology. [Updated 2026]. Available from: \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.nccn.org\/\" class=\"ng-star-inserted\" data-hveid=\"0\" data-ved=\"0CAAQ_4QMahgKEwjixcTjm8KUAxUAAAAAHQAAAAAQ3AQ\" target=\"_blank\"\u003ehttps:\/\/www.nccn.org\/\u003c\/a\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp data-path-to-node=\"52,3,0\"\u003eFood and Drug Administration (FDA). Cytoxan (Cyclophosphamide) Oral Tablets Prescribing Information \u0026amp; Toxicology Data. \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.google.com\/search?q=https:\/\/www.accessdata.fda.gov\/\" class=\"ng-star-inserted\" data-hveid=\"0\" data-ved=\"0CAAQ_4QMahgKEwjixcTjm8KUAxUAAAAAHQAAAAAQ3QQ\" target=\"_blank\"\u003ehttps:\/\/www.accessdata.fda.gov\/\u003c\/a\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2 data-path-to-node=\"53\"\u003eDisclaimer\u003c\/h2\u003e\n\u003cp data-path-to-node=\"54\" id=\"p-rc_0c1d5858219f45a0-36\"\u003eMedipoint India’s primary intention is to ensure\u003cspan class=\"citation-52\"\u003e\u003c\/span\u003e\u003cspan class=\"citation-52 citation-53 citation-end-53\"\u003e that its consumers get accurate, trustworthy, and expert-reviewed information. The contents of this website are for informational purposes only and are not intended to be a substitute for professional medical advice, diagnosis, or treatment\u003csup class=\"superscript\" data-turn-source-index=\"1\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan class=\"citation-52 citation-end-52\"\u003e. Please seek the advice of your doctor and discuss all \u003csup class=\"superscript\" data-turn-source-index=\"2\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003eyour queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on Medipoint India. Our mission is to support, not replace, the doctor-patient relationship.\u003c\/p\u003e","brand":"Medipoint India","offers":[{"title":"Default Title","offer_id":47891112362202,"sku":null,"price":350.0,"currency_code":"INR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0821\/2332\/5658\/files\/ADC0064_1.webp?v=1779087565","url":"https:\/\/www.medipointindia.com\/products\/adcyclo-50-tablets","provider":"Medipoint India","version":"1.0","type":"link"}