AROMASIN 25mg Tablet contains the active substance Exemestane. It belongs to a group of medicines known as Aromatase Inhibitors. It is primarily indicated for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is commonly prescribed after initial treatment with tamoxifen or as part of long-term hormonal therapy to reduce the risk of cancer recurrence.
Exemestane works by permanently blocking the aromatase enzyme responsible for estrogen production in postmenopausal women. By lowering estrogen levels, it helps prevent the growth and spread of hormone-dependent breast cancer cells.
AROMASIN 25mg Tablets should be used under the supervision of an oncologist and are intended only for postmenopausal women.
Uses of AROMASIN 25mg Tablets
Adjuvant treatment of early hormone receptor-positive breast cancer
Treatment of advanced breast cancer in postmenopausal women
Breast cancer treatment following tamoxifen therapy
Prevention of breast cancer recurrence
Long-term hormonal therapy in breast cancer management
Therapeutic Effects of AROMASIN 25mg Tablets
AROMASIN 25mg Tablets exert their therapeutic effect by irreversibly inhibiting the aromatase enzyme, which converts androgens into estrogen. This significantly reduces circulating estrogen levels, depriving hormone-sensitive breast cancer cells of the hormonal stimulation needed for growth and survival.
Interaction of AROMASIN 25mg Tablets with Other Drugs
It is important to inform your healthcare professional about all medications you are taking, including prescription drugs, supplements, and herbal products.
Notable interactions include:
Estrogen-containing medicines: May reduce the effectiveness of Exemestane.
Hormone Replacement Therapy (HRT): Should generally be avoided.
Rifampicin: May decrease Exemestane blood levels.
Phenytoin: May reduce treatment effectiveness.
Carbamazepine: May lower Exemestane concentrations.
Certain herbal supplements: May interfere with hormonal therapy.
More Information about AROMASIN 25mg Tablets
Keep out of reach of children and pets.
Store below 30°C in a cool and dry place.
Protect from moisture and direct sunlight.
Keep tablets in their original packaging.
Do not use expired medication.
How to Consume AROMASIN 25mg Tablets
AROMASIN 25mg Tablets are oral medications meant to be swallowed whole with a glass of water.
The tablet is usually taken once daily after a meal, preferably at the same time each day. Do not crush, chew, or break the tablet unless instructed by your doctor.
Safety Advice for AROMASIN 25mg Tablets
Breast Feeding
Unsafe / Contraindicated
AROMASIN is not intended for breastfeeding women and may harm the infant.
Alcohol
Caution
Alcohol may worsen certain side effects such as dizziness, fatigue, and bone loss.
Liver
Caution
Patients with liver impairment should use this medicine under medical supervision.
Kidneys
Caution
Patients with severe kidney disease may require careful monitoring.
Driving
Caution
AROMASIN may cause dizziness, weakness, or fatigue. Avoid driving if affected.
Pregnancy
Unsafe / Contraindicated
Exemestane may cause serious fetal harm and should not be used during pregnancy.
Side Effects of AROMASIN 25mg Tablets
Side effects are unwanted symptoms caused by medicines. Although not everyone experiences them, some patients may develop side effects.
Common Side Effects of AROMASIN 25mg Tablets
Hot flashes
Excessive sweating
Joint pain
Muscle pain
Fatigue
Headache
Nausea
Difficulty sleeping
Serious Side Effects of AROMASIN 25mg Tablets
Osteoporosis and bone fractures
Severe allergic reactions
Liver function abnormalities
Depression
Cardiovascular complications
Severe skin reactions
Word of Advice
Long-term treatment with AROMASIN 25mg Tablets may lead to decreased bone mineral density. Your doctor may recommend regular bone density scans (DEXA scans), calcium supplementation, vitamin D intake, and regular exercise to help maintain bone health. Report unusual bone pain, chest pain, severe weakness, or symptoms of liver problems immediately.
FAQs about AROMASIN 25mg Tablets
Q1. What is AROMASIN 25mg Tablet used for?
It is used for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
Q2. How does AROMASIN work?
It permanently blocks the aromatase enzyme, reducing estrogen production and slowing the growth of hormone-dependent breast cancer cells.
Q3. Why should AROMASIN be taken after meals?
Taking the medicine after food improves absorption and helps achieve optimal therapeutic levels.
Q4. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your normal schedule. Do not take a double dose.
Q5. Can AROMASIN affect bone health?
Yes. Long-term use may increase the risk of osteoporosis and fractures. Regular monitoring and preventive measures may be recommended.
Fact Box of AROMASIN 25mg Tablets
Molecule Name: Exemestane 25mg
Therapeutic Class: Antineoplastics / Hormonal Cancer Therapy
Pharmacological Class: Steroidal Aromatase Inhibitors
Indications: Early Breast Cancer, Advanced Breast Cancer, Post-Tamoxifen Therapy, Prevention of Breast Cancer Recurrence in Postmenopausal Women.
