PICASA Oral Suspension contains the active substance Posaconazole 40mg/ml. It belongs to a group of medicines known as Triazole Antifungal Agents. It is primarily used for the prevention and treatment of serious fungal infections, especially in patients with weakened immune systems such as those undergoing chemotherapy, bone marrow transplantation, or suffering from blood-related disorders. It is also used in the treatment of oropharyngeal candidiasis (oral thrush) and invasive fungal infections. (1mg.com)
Posaconazole works by inhibiting the production of ergosterol, an essential component of the fungal cell membrane. This damages the fungal cell membrane, preventing fungal growth and eliminating the infection. PICASA Oral Suspension should be taken exactly as prescribed by your healthcare professional.
Uses of PICASA Posaconazole Oral Suspension
- Prevention of Invasive Aspergillus Infections
- Prevention of Invasive Candida Infections
- Oropharyngeal Candidiasis (Oral Thrush)
- Invasive Aspergillosis
- Serious Fungal Infections in Immunocompromised Patients
- Fungal Infection Prevention During Chemotherapy or Stem Cell Transplantation
Therapeutic Effects of PICASA Posaconazole Oral Suspension
PICASA works by blocking the fungal enzyme responsible for ergosterol synthesis, an essential component of the fungal cell membrane. This weakens the fungal cell membrane, stops fungal growth, and helps eliminate the infection.
Interaction of PICASA Posaconazole Oral Suspension with Other Drugs
It is important to inform your healthcare professional about all medicines you are taking.
Notable interactions include:
- Rifampicin
- Phenytoin
- Carbamazepine
- Cyclosporine
- Tacrolimus
- Sirolimus
- Quinidine
- Certain Cholesterol-Lowering Medicines (Statins)
- Pimozide
More Information about PICASA Posaconazole Oral Suspension
- Keep out of reach of children.
- Store below 30°C.
- Do not freeze.
- Shake well before use.
- Keep the bottle tightly closed.
- Protect from direct sunlight and moisture.
How to Consume PICASA Posaconazole Oral Suspension
PICASA is an oral suspension and should be taken exactly as directed by your doctor.
- Shake the bottle well before each use.
- Measure the dose using the supplied measuring cup or syringe.
- Preferably take with food or a nutritional drink for better absorption.
- Complete the full prescribed course even if symptoms improve.
Safety Advice for PICASA Posaconazole Oral Suspension
Breast Feeding
Consult Your Doctor
Use only if prescribed during breastfeeding.
Alcohol
Consult Your Doctor
The interaction with alcohol is not clearly established.
Liver
Caution
Patients with liver disease require regular liver function monitoring.
Kidneys
Generally Safe
No routine dose adjustment is usually required in kidney impairment.
Driving
Caution
May cause dizziness or blurred vision. Avoid driving if affected.
Pregnancy
Use Only on Medical Advice
Use during pregnancy only if clearly needed and prescribed by your doctor.
Side Effects of PICASA Posaconazole Oral Suspension
Common Side Effects of PICASA Posaconazole Oral Suspension
- Nausea
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Fever
- Dizziness
- Loss of Appetite
Serious Side Effects of PICASA Posaconazole Oral Suspension
- Liver Dysfunction
- Severe Allergic Reactions
- Irregular Heart Rhythm (QT Prolongation)
- Severe Skin Reactions
- Low Potassium Levels
- Breathing Difficulties
